Tham khảo Eribulin

↑ https://www.accessdata.fda.gov/scripts/cder/ob/patent_info.cfm?Product_No=001&Appl_No=201532&Appl_type=N%5B%5D
↑ “FDA approves new treatment option for late-stage breast cancer” (Thông cáo báo chí). USFDA. 15 tháng 11 năm 2010. Truy cập ngày 15 tháng 11 năm 2010.
↑ Notice of Decision for HALAVEN[liên kết hỏng]
↑ https://www.fda.gov/downloads/drugs/developmentapprovalprocess/howdrugsaredevelopedandapproved/drugandbiologicapprovalreports/ndaandblaapprovalreports/ucm544019.pdf%5B%5D
↑ https://www.fda.gov/downloads/drugs/developmentapprovalprocess/smallbusinessassistance/ucm447307.pdf%5B%5D
1 2 FDA approves first drug to show survival benefit in liposarcoma. Jan 2016
↑ http://www.clinicaltrials.gov/ct2/results?term=eribulin+OR+E7389%5B%5D
↑ https://clinicaltrials.gov/ct2/show/NCT03207672?cond=E7389+Liposomal&rank=1%5B%5D
↑ Yu, Yanke; Desjardins, Christopher; Saxton, Phil; Lai, George; Schuck, Edgar; Wong, Y. Nancy (2013). “Characterization of the pharmacokinetics of a liposomal formulation of eribulin mesylate (E7389) in mice”. International Journal of Pharmaceutics. 443 (1–2): 9–16. doi:10.1016/j.ijpharm.2013.01.010. PMID 23313921.
↑ https://clinicaltrials.gov/ct2/show/NCT03222856?term=eribulin+and+pembrolizumab&rank=1%5B%5D
↑ Towle, M. J; Salvato, K. A; Budrow, J; Wels, B. F; Kuznetsov, G; Aalfs, K. K; Welsh, S; Zheng, W; Seletsky, B. M (2001). “In vitro and in vivo anticancer activities of synthetic macrocyclic ketone analogues of halichondrin B”. Cancer Research. 61 (3): 1013–21. PMID 11221827.
↑ Yu MJ, Kishi Y, Littlefield BA (2005). “Discovery of E7389, a fully synthetic macrocyclic ketone analogue of halichondrin B”. Trong Newman DJ, Kingston DGI, Cragg, GM (biên tập). Anticancer agents from natural products. Washington, DC: Taylor & Francis. ISBN 978-0-8493-1863-4.Quản lý CS1: nhiều tên: danh sách tác giả (liên kết)[cần số trang]
↑ Hirata, Y; Uemura, D (1986). “Halichondrins - antitumor polyether macrolides from a marine sponge”. Pure and Applied Chemistry. 58 (5): 701–710. doi:10.1351/pac198658050701.
↑ Bai, R. L; Paull, K. D; Herald, C. L; Malspeis, L; Pettit, G. R; Hamel, E (1991). “Halichondrin B and homohalichondrin B, marine natural products binding in the vinca domain of tubulin. Discovery of tubulin-based mechanism of action by analysis of differential cytotoxicity data”. The Journal of Biological Chemistry. 266 (24): 15882–9. PMID 1874739.
↑ Jordan, M. A; Kamath, K; Manna, T; Okouneva, T; Miller, H. P; Davis, C; Littlefield, B. A; Wilson, L (2005). “The primary antimitotic mechanism of action of the synthetic halichondrin E7389 is suppression of microtubule growth”. Molecular Cancer Therapeutics. 4 (7): 1086–95. doi:10.1158/1535-7163.MCT-04-0345. PMID 16020666.
↑ Okouneva, T; Azarenko, O; Wilson, L; Littlefield, B. A; Jordan, M. A (2008). “Inhibition of centromere dynamics by eribulin (E7389) during mitotic metaphase”. Molecular Cancer Therapeutics. 7 (7): 2003–11. doi:10.1158/1535-7163.MCT-08-0095. PMC 2562299. PMID 18645010.
↑ Smith, Jennifer A; Wilson, Leslie; Azarenko, Olga; Zhu, Xiaojie; Lewis, Bryan M; Littlefield, Bruce A; Jordan, Mary Ann (2010). “Eribulin Binds at Microtubule Ends to a Single Site on Tubulin to Suppress Dynamic Instability”. Biochemistry. 49 (6): 1331–7. doi:10.1021/bi901810u. PMC 2846717. PMID 20030375.
↑ Wilson, Leslie; Lopus, Manu; Miller, Herbert P; Azarenko, Olga; Riffle, Stephen; Smith, Jennifer A; Jordan, Mary Ann (2015). “Effects of Eribulin on Microtubule Binding and Dynamic Instability Are Strengthened in the Absence of the βIII Tubulin Isotype”. Biochemistry. 54 (42): 6482–9. doi:10.1021/acs.biochem.5b00745. PMID 26435331.
↑ Kuznetsov, Galina; Towle, Murray J; Cheng, Hongsheng; Kawamura, Takanori; Tendyke, Karen; Liu, Diana; Kishi, Yoshito; Yu, Melvin J; Littlefield, Bruce A (2004). “Induction of Morphological and Biochemical Apoptosis following Prolonged Mitotic Blockage by Halichondrin B Macrocyclic Ketone Analog E7389”. Cancer Research. 64 (16): 5760–6. doi:10.1158/0008-5472.CAN-04-1169. PMID 15313917.
↑ Towle, M. J; Salvato, K. A; Wels, B. F; Aalfs, K. K; Zheng, W; Seletsky, B. M; Zhu, X; Lewis, B. M; Kishi, Y (2010). “Eribulin Induces Irreversible Mitotic Blockade: Implications of Cell-Based Pharmacodynamics for in vivo Efficacy under Intermittent Dosing Conditions”. Cancer Research. 71 (2): 496–505. doi:10.1158/0008-5472.CAN-10-1874. PMID 21127197.
↑ Funahashi, Yasuhiro; Okamoto, Kiyoshi; Adachi, Yusuke; Semba, Taro; Uesugi, Mai; Ozawa, Yoichi; Tohyama, Osamu; Uehara, Taisuke; Kimura, Takayuki (2014). “Eribulin mesylate reduces tumor microenvironment abnormality by vascular remodeling in preclinical human breast cancer models”. Cancer Science. 105 (10): 1334–42. doi:10.1111/cas.12488. PMC 4462349. PMID 25060424.
↑ Yoshida, T; Ozawa, Y; Kimura, T; Sato, Y; Kuznetsov, G; Xu, S; Uesugi, M; Agoulnik, S; Taylor, N (2014). “Eribulin mesilate suppresses experimental metastasis of breast cancer cells by reversing phenotype from epithelial–mesenchymal transition (EMT) to mesenchymal–epithelial transition (MET) states”. British Journal of Cancer. 110 (6): 1497–505. doi:10.1038/bjc.2014.80. PMC 3960630. PMID 24569463.
↑ Kawano, S; Asano, M; Adachi, Y; Matsui, J (2016). “Antimitotic and Non-mitotic Effects of Eribulin Mesilate in Soft Tissue Sarcoma”. Anticancer Research. 36 (4): 1553–61. PMID 27069131.
1 2 Laughney AM, Kim E, Sprachman MM, Miller MA, Kohler RH, Yang KS, Orth JD, Mitchison TJ, Weissleder R (2014). “Single-cell pharmacokinetic imaging reveals a therapeutic strategy to overcome drug resistance to the microtubule inhibitor eribulin”. Science Translational Medicine. 6 (261): 261ra152. doi:10.1126/scitranslmed.3009318. PMC 4330962. PMID 25378644.
↑ Kim, Dae-Shik; Dong, Cheng-Guo; Kim, Joseph T; Guo, Haibing; Huang, Jian; Tiseni, Paolo S; Kishi, Yoshito (2009). “New Syntheses of E7389 C14−C35 and Halichondrin C14−C38 Building Blocks: Double-Inversion Approach”. Journal of the American Chemical Society. 131 (43): 15636–41. doi:10.1021/ja9058475. PMID 19807076.